Area code 21 in Paraguay serves the capital city of Asunción and its metro area known as Great Asunción, which encompasses the cities of San Lorenzo, Fernando de la Mora, Luque, Mariano Roque Alonso, and Lambaré. Home to over 2 million people, Great Asunción is the most important urban center in the country and acts as a base for the majority of businesses with a presence in Paraguay.